Stephen Senn: Blogs and Web Papers

This page provides a link to various blogs of mine and also to papers of mine that are readily available on the web. On the whole the papers are didactic in nature.

A companion page on Data Sets may also be of interest

Blogs and Papers

https://www.linkedin.com/pulse/being-consultant-medical-statistician-stephen-senn/?trackingId=QNdBkRudTHuftxgUour92g%3D%3D
Type Topic Title Keywords
Blog Evidence Based Medicine It's publishing, Jim, but not as we know it Publication bias; open data
Blog Evidence Based Medicine Fishing for Fakes with FisherFraud; Randomisation
Paper Evidence Based Medicine Publication Bias: Editors are not Blameless after allPublication bias
Paper Evidence Based Medicine Authors are also reviewersPublication bias
Paper Evidence Based Medicine Overstating the EvidenceMeta-analyis; Standard Errors
Paper Evidence Based Medicine Sharp tongues and bitter pillsEthics; Pharmaceutical industry; Meta-analysis; Publication bias; Conflict of Interest
Blog Evidence Based Medicine Open seasonData-sharing
Blog Evidence Based Medicine Is Pooling FoolingMeta-Analysis
Blog Evidence Based Medicine Bad PharmaPharmaceutical industry; Ethics; Missing data; Data filters
Blog Experimental Design Delta ForcePower; Sample size; Clinical trials
Blog Experimental Design Rothamsted Statistics meets Lord's ParadoxCausal Analysis; Components of Variation; Analysis of Variance
Blog Experimental Design On the LevelCausal Analysis; Components of Variation; General Balance;Block Structure; Analysis of Variance
Blog Experimental Design To Infinity and BeyondBig data; Clinical trials; Randomisation; Standard Error; Analysis of Variance
Blog Experimental Design Red Herrings and the Art of Cause FishingCausal Analysis; Components of Variation
Paper Experimental Design The Misunderstood PlaceboEthics; Control; Clinical Trials; Equipoise
Blog Experimental Design Fooling the Patient: an Unethical Use of Placebo?Ethics; Control; Clinical Trials; Equipoise
Blog Experimental Design Placebos: It's not only the Patients that are FooledEthics; Control; Clinical Trials; Equipoise
Paper Experimental Design The AB/BA Cross-over: How to perform the two-stage analysis if you can't be persuaded that you shouldn't Cross-over Trial; Clinical Trials; Carry-Over; Testing Assumptions; Inference
Paper Experimental Design An Incomplete Blocks Trial in Asthma Cross-over Trial; Clinical Trials;Incomplete Blocks; Dose-Finding; Inference Parallel Assay
Paper Experimental Design Lessons from TGN 1412 Clinical Trials; Dose-Finding; Ethics; Trend Effects; Inference; First-in-Man
Paper Experimental Design Safety First Clinical Trials; Dose-Finding; Ethics; Trend Effects; Inference; First-in-Man
Blog Experimental Design Blood simpleBioequivalence; Two-sided tests; One-sided tests; Clinical Trials; Confidence Intervals
Blog Experimental Design Making it personal: N-of-1 trials, allowing for individuality but not overdoing itClinical Trials; Random Effects; Shrinkage; Mixed Models;Personalised Medicine
Paper History Cushny and Peebles, optical isomers, and the birth of modern statistics. Student; t-test; n-of-1 trials
Paper History A century of t-tests Student; t-test; n-of-1 trials
Paper History The t-test tool Student; t-test; n-of-1 trials
Paper History Francis Galton and Regression to the Mean Genetics; Correlation
Paper History Tea for three. Fisher; Randomisation; Blinding; Experimental Design; Inference
Blog Inference Automatic for the people Bayes Factors; Two Trials Rule; Significance
Blog Inference Dawid's Selection Paradox Bayesian; Conjugate Prior; Hierarchical Model
Blog Inference A Paradox of Prior ProbabilitiesBayesian; Conjugate Prior; Hierarchical Model
Blog Inference Fisher's Alternative to the AlternativeHistory of Statistics; Significance Test
Blog Inference Also Smith and Jones Bayesian; Sequential Analysis
Blog Inference The irrelevance of stopping rules in meta-analysisSequential Analysis; Meta-Analysis; Weighting; Evidence
Blog Inference The Pathetic P-valueBayesian; Frequentist; Significance
Blog Inference Double JeopardyBayesian; Frequentist; Significance
Blog Inference When relevance is irrelevant Additivity; Statistical Analysis; Survival Analysis; Numbers Needed to Treat; Personalised Medicine
Paper Inference Bayesian, Likelihood,and FrequentistApproaches to Statistics Tutorial; Bayesian; Frequentist; Clinical Trials; Drug Development
Paper Inference Invalid Inversion Regression to the Mean; Error of the Transposed Conditional; Bayesian
Paper Inference You may Believe you are a Bayesian but you are Probably Wrong Bayesian; Jeffreys; Fisher; De Finetti; Neyman-Pearson
Blog Inference The nuisance parameter nuisance Cross-over trials; Testing assumptions; Pre-testing; Carry-over
Blog Inference The importance of knowing how much you don't know Standard Errors; History of Statistics; Meta-analysis; Confidence Intervals;Experimental Design
Blog Inference Of Amazons, Martingales, Rogue Traders and Sequential Analysis Meta-analysis; Sequential Analysis; Martingales;Clinical trials
Paper Miscellaneous Comets, Contagion and ContingencyInfectious diseases; Stochastic Processes; Cometary Hypothesis
Blog Personalised Medicine Personal Perils Numbers Needed to Treat; Precision Medicine; Personalised Medicine
Blog Personalised Medicine 30 Years of Numbers Needed to TreatNumbers Needed to Treat; Precision Medicine; Personalised Medicine
Blog Personalised Medicine Painful Dichotomies Numbers Needed to Treat; Precision Medicine; Personalised Medicine; Exponential Distribution; Counterfactual
Program Personalised Medicine NNT Simulator and Calculator Numbers Needed to Treat; Precision Medicine; Personalised Medicine; Exponential Distribution; Counterfactual
Blog Personalised Medicine Responder Despondency Numbers Needed to Treat; Precision Medicine; Personalised Medicine; Exponential Distribution; Counterfactual; Zombie Statistics
Paper Personalised Medicine Statistical pitfalls of personalized medicine Numbers Needed to Treat; Precision Medicine; Personalised Medicine; Exponential Distribution; Counterfactual; Zombie Statistics
Paper Personalised Medicine Three Things Every Medical Writer Should Know About Statistics Regression to the Mean; Invalid Inversion; Precision Medicine; Personalised Medicine;
Paper Personalised Medicine Mastering Variation Numbers Needed to Treat; Precision Medicine; Personalised Medicine; Exponential Distribution; Counterfactual; n-of-1 Trials
Blog Personalised Medicine Evidence Based or Person-centred? A Statistical debate (Guest Post) Precision Medicine; Personalised Medicine; Bioequivalence; n-of-1 Trials
Blog Professional On Being a Consultant (Medical) Statistician Consulting; Pharmaceutical Industry
Blog Randomisation Randomisation, Ratios and RationalityClinical Trials; Analysis of Variance; Randomisation
Paper Randomisation The Well-adjusted StatisticianClinical Trials; Analysis of Covariance; Randomisation
Blog Randomisation Being a statistician means never having to say you are certain Clinical Trials; Analysis of Variance; Randomisation; Causal Analysis
Blog Randomisation Indefinite IrrelevanceClinical Trials; Analysis of Variance; Randomisation; Causal Analysis
Paper Randomisation Baseline Balance and Valid Statistical AnalysesClinical Trials; Analysis of Variance; Randomisation
Blog Randomisation Stop Obesessing about BalanceClinical Trials; Analysis of Variance; Randomisation
Blog Randomisation Being Just about AdjustmentClinical Trials; Analysis of Covariance; Randomisation; Baselines
InterviewRandomisation 70 Years and Still Here: The Randomized Clinical Trial and its CriticsClinical Trials; Analysis of Variance; Randomisation
BlogRandomisation Randomisation is not about balance, nor about homogeneity but about randomnessClinical Trials; Analysis of Variance; Randomisation, Incomplete blocks, Confidence Intervals
BlogRandomisation Balance is not the issueClinical Trials; Analysis of Variance; Randomisation; Incomplete blocks; Confidence Intervals
BlogRandomisation Losing controlClinical Trials; Analysis of Variance; Randomisation; Concurrent Control; Historical Controls; COVID-19
BlogTeaching On thinking and learningUniversities; Undergraduate Education
ProgramTeaching Logistic exam mark rescalerExaminations; Assessment; Logistic Regression

Page of links to Stephen Senn's Statistics notes

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This page last updated 20 October 2020

Page maintained by Stephen Senn stephen@senns.uk